I sincerely appreciate your consideration. The test result only means that you did not have COVID-19 at the time of testing. Thank you for the advice Kyra! I’m currently 33 weeks pregnant. This means approximately 37.4% of the population has O positive blood. In my family of origin I am the eldest of five surviving siblings, four girls and 1 boy, with one additional sibling dying at or before birth between each of us for a total of nine children between my parents. I am wondering, can two positive kell people have children together? I am not sure why. There are apparently quite a few antigenic things that can be running around on the surface of your red blood cells. The Kell antibody was introduced into your system, and Daddy is also negative, so as far as I can tell there is no way your son inherited the genes to produce Kell antigens. If it DOES inherit the Kell bloodtype then your body will attack it again. Seriously, and no sugarcoating, there is no real reason to think the kids aren’t biologically your progeny. Now, we’ve all met families where all the kids were the same gender, so you know 50/50 doesn’t mean it will always split down the middle between two outcomes. the baby has kell positive plus anti kell antibodies? The Kell antigens are K, k, Kp a, Kp b, Js a and Js b. Thanks! What does it mean when a baby is coombs positive? My hubby tested positive for kell antigen and is homogenous for kell so all our kids are kell positive , can you please explain how he is homogenous for kell antigen , my pregnancy is now 34 weeks and my tillers have remained stable at 1:28 but today have doubled , baby shows no signs of anaemia via mca scan and no signs of hydrous but they want to deliver in 2 weeks , what does the rise in antibodies mean? I wrote you earlier, but my blog didn’t post it. During a transfusion or delivery if that person is exposed to the antigen then antigen antibody Reaction occurs. Maybe it is on your post it is pretty late. I am anti-k (little k, used to be called cellano). I did have a transfusion. If he carries one gene, we have 50% chance that he passed it on to her, and if he has two, 100% chance she is KELL positive. I hope he is not Kell positive, but I have to tell you that yes he could be. I’m female with the normal blood type O+ So to recap antigens are on the RBcs and antibody is the plasma. Their children have the potential genotypes of: We know two things from these squares and the fact Kell positive blood is rare. Usually the blood is taken from the baby’s cord while it is attached to the placenta following delivery. What does kell mean? Or am I not understanding this at all? If you are antigen typed and are Kell positive this means you cannot make a antibodies to Kell. Hoping that it will help young girls/women of childbearing age. However, your sibling’s birth is unusual because there should have been enough alloimmunization to effect the pregnancy. If your fetus is Kell+ your body will not attack it because it is the same as your blood type. Think of the protein as the “foundation” the K, k, K3, and many other Kell system antigens “houses sit” on. They’ll need to get tested, because your daughters will have no reproductive issues, if your son has the Kk then his reproductive partner’s Ob/Gyn will need to know to keep a close eye on her pregnancies. However, any subsequent pregnancies will be threatened if the fetus is Kell positive. You are not a “freak”. It means that a blood test, called a Coombs test, or Direct Antibody Test (DAT), was done on your baby and was positive. So if she becomes pregnant with a Kell-positive baby, her anti-Kell antibodies might cross the placenta and destroy the baby’s red blood cells. Hence I said no more hospitals with my second birth! 2nd pregnancy I had kell antibodies but since Dad is Neg and my pregnancy went on as normal. It sounds like everything will be good, though, so try to stay calm. Kell would have also showed up on your initial blood test. Which means ONE (which one is anyone’s guess and it would take bloodtyping to find out) of your former pregnancies had a Kell positive fetus. This means there is a 91% chance your husband is kell negative too! Can anyone please shed some light on whether I have antigens or antibodies. I was diagnosed Kell positive when I was in my 20.’ My wife at the time had 6 miscarriages. This seemed to surprise the doctor who offered no explanation as to why in our visit. I appreciate your help. My husband has been tested and he is Negative for K (Kell), positive for k (cellano). If you test positive for COVID-19—or suspect that you have it—it is important that you follow recommendations from the Centers for Disease Control and Prevention (CDC) to stop the spread. The antibodies are usually made after a blood transfusion.. I almost died having my son. READ MORE. I contracted the Kell antibody because of a blood transfusion I had after my 1st pregnancy which was a c-sec. I have the antibody and my husband is Kell positive (I formed the antibodies from my first born.). (noun) Dictionary ! If he has kk, then it’s all clear because he cannot give any offspring the Kell antigen gene. I did indeed *almost* die in the womb, and the Obstetrician said I probably wouldn’t live very long after birth at the rate things were going. If I am Kell +, & My husband is Kell -, babies + or – is currently unknown . It would have been that the other pregnancies had Kell negative babies. My sincere hopes for your future reproductive success. After losing two pregnancies, I was blessed with three healthy babies in a row. If the fetus is Kell- then there is no antigen there to cause your body to have alloimmunization. What happens if I don’t pass it on to the fetus and I’m positive but fetus is negative? I am sorry, but I am not a doctor, so I may be no help at all. So does that mean that the baby 100% will not have it and I don’t have to worry about a single thing? 2) All four kids are K positive. I am so sorry about the delayed reply. Hi have three boys after the first I had a blood tranfution went on two baby number two at 37 week they found out that i was kell postive but was not informed about it went on to baby three and found out at 17 wèek blood test that I was had kell postive partaner is negative what dose this mean for future pregnants and for the future of the three boys. I was thinking maybe my grandson’s mother should get tested just in case. I absolutely LOVE your historical research, as a geneology nerd myself it makes me happy. Try not to worry. Odds are good your body will always make enough red blood cells for you. If the mother is Kell positive but the dad is not Kell positive, then the fetus will be unharmed by the mother’s body either way. I know this because the pregnancy and baby were completely normal.i am expecting again and dad has not been tested yet.i was just wondering if there is a chance he could be kell postive after 7 healthy pregnancy and babies .all same dad? So as I understand all my other babies were kell negative and if this baby is kell postive my body will give this baby a chance ? Your daughter should have no issues (related to blood type) and your son’s partner (if he chooses to have kids as adult and falls in love with a reproductively viable woman!) Multiple pregnancy losses are agonizing to go through, but more common than people realize. Kell may become more common now. Advice… Other articles have told me that the antigen is very common, while the antibody is not so much. My OB says my blood is normal. Kell is not a blood type; it is one (among many things) that attaches to some peoples blood cells. You’re actually Kk, which means you have a Kell+ gene and one without it. Thanks for any info!!! If the baby does have the cellano gene, then your titers will start to show it and the doctors can respond as needed. Moreover, random chance can make a dominate gene go bye-bye even when the dominate gene doesn’t cause the death of many offspring who inherit it. In other words, please do not sugarcoat or downplay the possibility for fear that this could set some sort of disruptive chain of events in a family’s life somewhere. Sensitisation occurs when the mother is exposed to RhD positive blood for the first time and develops an immune response to it. (I’m not sure I even asked these questions correctly). Hi there, I just got my first blood test result, it says I have anti K(ell) antibodies. I am not a medical doctor, only a medical anthropologist, and I can but speculate that your first born had a K+ blood type and now you have antigens that will attack any K+ tissue, including another Kell+ fetus. How did I not get weeded out of the genetic pool generations ago. . yesterday we just came back from my 2nd visit to a specialist. What I am also wondering is are the Kell antibodies only detectable if the baby in fact has the antigen, or are they detectable even when basically dormant. B Positive Blood Type (B+) 1. It took a toll on our relationship. There was always speculation that her children were actually Henry VIII’s. My wife and I have a son (Kell blood type unknown) and we have just found out my wife is pregnant again. We did not know anything about this until we were tested for genealogy purposes and I only tested two of my sons, so it would behoove us to get everyone tested as well as my grandson. But in some breast cancers, the HER2 gene produces too many proteins. So no, it is not rare. (adsbygoogle = window.adsbygoogle || []).push({}); Post was not sent - check your email addresses! Debbie from NY. This is how immunohematology is performed on the antigen antibody reaction. My daughter is pregnant with twins and both have the Kells genes (when she had her first baby. Some people have it; some don’t. If your baby appears severely affected, blood transfusions, given to your baby while he’s still in utero, can help prevent harm to baby. If he is indeed homozygous then I have no idea whatsoever why your other pregnancies didn’t have severe complications. OB/Gyns tend to overcompensate on preventatives. I am currently in the same situation and am totally baffled! What this means is you can place your iPhone on a wireless charging pad and the iPhone would charge wirelessly without having to connect a charger. If it is a first pregnancy, then the mother’s body will not attack the fetus even if it is Kell positive. Hi, I am very, very glad baby #9 is doing well and I hope he or she has zero problems before, during, or after the birth. I am A- with Kell and Kidd antibodies. The test looks for … I am pregnant and diagnosed as having the anti-Kell antigen. Since there is only a 50/50 of a first born getting the K gene, maybe only 2 out of the 16 hypothetical grandchildren will be Kell positive. This does not, sadly, rule out any other disaster — but from the Kell end of things you should be fine. Thank you! Can you post back here and tell me if all is well or not? I think it would have to be a deficient immune response by your own body and I have no knowledge about that topic. Would my body make the anti-kell show up even if daddy is negative? Hope all turns out well — Kyra. About 500 members… So helpful!!y. Not only Rh-, m-n- and KK? Exposure to Kell causes one to develop Anti-Kell, but Kell itself is a genetic trait. First, homozygous Kells (KK) is very, very rare. Le système Rhésus est un système complexe qui comporte plusieurs antigènes dont le plus important pour la transfusion est l’antigène D. Sur les globules rouges des sujets dits Rhésus négatifs l’antigène D n’est pas présent alors qu’il l’est chez les sujets Rhésus positif. I say that it’s more look like a woman with a blood type of “-” marrying a man with blood type “+”. There you have it. I hope your wife is anti-Kell antigen-free and all proceeds smoothly with a healthy, happy baby! As I am spending a fortune on fertility treatments, and have had every other test in the book done, I would like to find out if the Kell and other antigens/antibodies could have caused the problem. … If you love him, marry him. After all, it is a 50/50 shot, so you have an equal chance of non-Kell genes. Kell is definitely one of the most aggressive but with trained maternal fetal medicine specialist Kell positive babies have a fighting chance. Years later they had another child, also Kk. And yet, 38 years later, here I am. Your child will have inherited her RhD positive status from her RhD positive dad (NHS 2018, NICE 2008a). Please understand, I have thought long and hard about this before posting… whatever the answer, the outcome will not end my marriage. First, I think s/he is correct about your blood work being normal. I feel like even if the baby is negative and so is my husband that there could still be problems with myself? I’m trying to understand what it means that I’m K+k+. I wish we had the $ for the full bloodwork for my husband, as we are only finding put of he is positive or negative for the antigens. And after my second one (a week later) I had blood work done and it came back that I had Anti Kell. For simplicity’s sake we’ll say brown eyes are “B” and blue eyes are “b”. I have had every other known test done to determine the issue, so would like to put my mind at ease or proceed with sperm donation which both my partner and I are open to if this is indeed an issue for us. However, a wise doctor would panic and NOT push the issue … just in case. I’m also going to add a futer amnio should be done by a MFM @ 15-18 wks. Dear Melanie! Your birth with no complications is usual, in that the first pregnancy is almost always “safe” provided there is no blood transfer. If your body had a really strong response vis-a-vis antigens, then only your body can handle your blood, plasma, ect … Also, a really strong anti-Kell response by your body might indicate a significant risk for your next fetus, in spite of all the medical technology, if it is Kell positive too. Your daughter will not be troubled by Kell+ because her body will not attack the fetus either with or without Kell. Thanks for your help! Once you get a bb in the mix those little b genes are lurking in every gonad. This exact scenario actually happened to me. Yes, Rh and Kell antibodies are a concern because tend to be relatively immunogenic and cause more severe hemolytic disease of the newborn because they are expressed by a fetus so early and women lose babies. Once you are sensitized you can be too low to titer but should you get pregnant again w a K+ baby chances are your body will will have the same reaction. Well, tune in next post for the exciting adventures of Genealogy Quest! Did they double check? And generally, that’s not a problem. I didn’t have them in my first and haven’t had a transfusion. Has he been phenotyped. We also don’t know if the baby is definitely negative if antibodies have shown up in the first place…. Who knew? There are apparently quite a few antigenic things that can be running around on the surface of your red blood cells. I got really sick with a rare blood disease and had to deliver the babies at 18 weeks (worst thing I have ever done). He was K+. But, note that not all of the … Everyone would have two of these genes, so people with Kell positive blood are either “KK” or “Kk”, and people with Kell negative blood are “kk”. I am little k cellano negative O positive is it hard for me to get blood if needed, please reply as I will need a operation soon I am little k negative o positive Even if genetically otherwise they SHOULD express K or k, they don’t or barely do. I’m glad all the other pregnancies were healthy!). Once she’s exposed, she develops anti-Kell antibodies, which can attack and destroy Kell-positive red blood cells. It can be used in many aspects, referring to: what, how much or how high one gets. It is rare my midwife said to find blood compatible with Kell. I went through my last pregnancy (4th child) and had MCA scans, and my baby girl was born healthy and not anemic. Anxiety is hard on the mother and fetus too. That episode stressed me out a lot I had to ask my parents about it without telling them Im pregnant… but im glad it was just a mistake. Okay, the odds that your bloodwork gave a false negative is MUCH higher than the odds of any kids being not yours. What does it mean if I'm rhesus negative? And even if he DID have the Kell gene, there is lots they could do for his future reproductive partner, and many people with K+ men get lucky and get 3 Kell negative babies in a row. Either way, your babies are safe from issues due to Kell. Debbie , New York. Moreover, they only consider it odd enough to start testing things if you lose 3 babies in a row. He is the father of my two boys, and this third pregnancy where these antibodies have shown up for the first time. This pregnancy would be the first fetus after a kell positive pregnancy to have the Kell antigen, so it would be your SECOND Kell positive baby. Now I have anti-kell showing up on my blood test. Sometimes it is taken from the baby. 2. If mom’s brown eyes are Bb, then some of the kids might be blue-eyed, but the brown-eyed kids are all going to be carrying a recessive too. If your sons know they are carrying the Kell gene, then their partners can give the docs an early heads-up. It is an antigen on the red blood cell. Are they overrated or is it a big deal? My ancestry is all European (mainly British) but my Kell result is K+k+ (and also Kp(a-b+)). Hope that helps!!! but my husband is still worried about the babys health and how my health will fare. To have Kell positive blood means you have at least one of the Kell antigens on your red blood cells. The doctor told me that my anemia is not the same as the baby’s anemia, as you and your baby do not share the same blood. Thanks so much for getting back to me.my titer level is 1.8 which is pretty high. I have no IDEA how the body’s immune system can by ‘twisted’ to decry you as a person or mother; it would take extreme asshattery on the part of your husband’s family. thanks. Thank you again, this has been a struggle for many years to figure out what all this means. I love my wife and my kids, regardless of their origin. What blood tests do I need during pregnancy? I hope your pregnancy is a very, VERY healthy one with no complications. Will this be a health problem for me later in life. So of you are Kk, then are you positive or negative? What are some viable reasons these antigens could be in her system? With McLeod that foundation is malformed, thus the “houses” are missing or weak. How can that be? An indirect climbs test is the same thing as an antibody screen so since your indirect coombs is negative this means you are not expressing any antibodies. Should my worries stop or is their any threats to my baby girl?.thank u so much. If you only have two or three children, you may never even have a Kell-effected pregnancy, because you might have the good luck that the babies never get your husband’s genes. We won’t know if he is heterozygous or homozygous, but hopefully he will be negative and that will be the end of it. Your body recognized the foreign part of the blood (Kell) and built up antibodies to get rid of it… In the same way your body builds up antibodies to get rid of an infection. (obsolete) The caul. There is unlikely to be any insurmountable obstacles preventing your from having children … it may just take longer and be harder. Kell is not a blood type. I am currently 18 weeks pregnant. When my husbands blood came back, he is kell negative. The best news is that there is a lot they can do nowadays to keep a Kell+ fetus healthy until birth. Your son will be fine . Your first pregnancy will not be affected by kell antigens (but could still be one of the 1/3 lost pregnancies; there are lots of things that can go wrong with a normal pregnancy). KK people are VERY rare. This is my first pregnancy after a year of trying (about 7 weeks now) and I am very worried…Do you have any advice for me please? I am so sorry that I can’t be more help. If he is KK then they will definitely have the Kell antigen. What is the Kell factor and how do I get tested for it. I never had any blood transfusions or other pregnancies in my life, could I get this from my parents or husband? As far as we know I am the only one in my family that has this. Is that possible? Sorry, your blog cannot share posts by email. But after reading this I can’t believe how this problem it has become a nightmare to many moms. There are still a lot of issues that medical science doesn’t have all the answers for and there are things they are finding out about blood antigens everyday. My older sister and my younger half-brother and I all inherited his Kell. I’ve heard stories of Kell making you severely anemic, and causing women to bleed out even in cases where baby is negative. I would encourage you if you are ever hospitalized to be sure that you tell your nurses and doctors that you have an antibody. I am now 18 weeks pregnant, and my dr said since my husband is Kell negative and I’m anti-k (as opposed to anti-K), then we can do monthly titer scores until my numbers reach 1:16, then do MCA scans if necessary. If two couples, let’s name them Ted (BB) & Alice (bb) and Bob (bb) & Jane (Bb), have children who marry each other then it is possible that all their grandchildren can have blue eyes in spite of the fact that two grandparents have the dominate brown-eyed gene. However, not all of the ethnic groups share the same proportions of blood types. However, I am currently pregnant and am wondering how it could possibly effect my pregnancies. Nor is she is a drug user. How have I got these antibodies? Sperm meets Ms. Beings you did NOT mention a transfusion it is likely your husband is a carrier. People who have that blood have golden blood to me. I hope you get good news!! Things I know — it is rare, but anti-K antibodies can show up in a first pregnancy, so you aren’t alone. IGG antibodies cross the placenta and therefore if the baby has the antigen then a reaction occurs. and where that came from? O positive blood type is about 37% in Caucasians, 47% in African American, 53% in Hispanic, and 39% in Asian. I had to get a blood transfusion after. O genes … I too became anti-kell from a blood transfusion. I am sure the doctors are taking all reasonable precautions, tho. They all have irregular antibodies. Antibodies are found in serum/plasma. Of course, all of them could have brown eyes – it depends on the roll of the genetic dice when Mr. This is such a scary thing. My husbands blood work came back negative for the kell antigen. The presence of Kell antibodies can be detected by maternal blood testing. I have some friends that I am trying to work with to petition some how to get blood Donors screened for kell. I sincerely hope this reply finds you well and delivered of a healthy second child!!!!! I have a 3 year old daughter and my blood test was negative for anti kell antibodies when I had her. For a few years I’ve been wondering how many other women.. Many thanks in advance for any advice. That means all the children except for the first, your daughter, and #9 will be almost axiomatically Kell negative. A person can have a specific antibody but at the time of testing it may not be expressing itself and therefore the antibody screen is negative. The only way to know if she has the anti-Kell antigens is to go to an Ob/Gyn and get the blood tests done to detect them. Our mothers are both O+ Kell-. I agree with the petition. I can’t have blood transfusions unless they have an exact match as me. My wife is pregnant with our fourth child and has had three prior C Sections. It depends on 1) what kind of health care you can get and 2) luck. This response is inaccurate. I have the same situation as you, during the 6-th pregnancy it appeared I have Kell antigens. Would I be safe assuming that my first daughter would be kk and my son kk and my youngest child Kk ? i found out about 2 months ago that i have the kell anti-body. Also, there are HUNDREDS of antigens a partner could pass to baby that mother doesn’t have– many in the Rh system, Kell system, Kidd system, Duffy, Dombrock, etc. Forgot to post this; my apologies for the delay). Thank in advance. Early delivery might also be necessary. Body will attack it again again but lost the baby does have the Kells genes when! Their kids of this antigen? waiting for my husband quickly went in to get his blood and... 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